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and L2 T has the following structure IV wherein R6 is selected from aryl, C3 C7 cycloalkyl, and heteroaryl, each of which is optionally substituted with one or more substituents selected from C1 C4 acylthio, C2 C4 alkenyl, C1 C4 alkyl, C1 C4 alkylamino, C1 C4 alkoxy, amino, amino C1 C4 alkyl, halo, C1 C4 haloalkyl, hydroxyl, hydroxy C1 C4 alkyl, and thio, wherein C2 C4 alkenyl, C1 C4 alkylamino and C1 C4 alkoxy are further optionally substituted with one substituent selected from C1 C4 alkylaryl, hydroxyl, and thio; R7 and R8 are each independently H or C1 C6 alkyl; R9 is C1 C6 alkyl or thio; R10 is selected from optionally substituted alkyl, optionally substituted alkylamino, optionally substituted cycloalkyl, optionally substituted aryl, optionally substituted heterocyclyl, optionally substituted heteroaryl, COR27, CSR27, OR27, and NHR27, wherein each R27 is independently optionally substituted alkyl, optionally substituted alkylamino, optionally substituted cycloalkyl, optionally substituted aryl, optionally substituted heterocyclyl, or optionally substituted heteroaryl; and each AA is independently an amino acid; n is an integer from 0 to 25; L4 is the remaining portion of linker L2 or is absent; T is said targeting moiety; wherein the NH group bonded to R10 in Formula X forms a junction peptide bond JPB with AA1 in Formula VI, wherein the JPB is enzymatically cleavable, and wherein AA1 AA, taken together comprises an amino acid sequence capable of facilitating enyzmatic cleavage of said JPB <a href=https://acialis.sbs>cialis generic cost</a> can i get a refund for it
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and L2 T has the following structure IV wherein R6 is selected from aryl, C3 C7 cycloalkyl, and heteroaryl, each of which is optionally substituted with one or more substituents selected from C1 C4 acylthio, C2 C4 alkenyl, C1 C4 alkyl, C1 C4 alkylamino, C1 C4 alkoxy, amino, amino C1 C4 alkyl, halo, C1 C4 haloalkyl, hydroxyl, hydroxy C1 C4 alkyl, and thio, wherein C2 C4 alkenyl, C1 C4 alkylamino and C1 C4 alkoxy are further optionally substituted with one substituent selected from C1 C4 alkylaryl, hydroxyl, and thio; R7 and R8 are each independently H or C1 C6 alkyl; R9 is C1 C6 alkyl or thio; R10 is selected from optionally substituted alkyl, optionally substituted alkylamino, optionally substituted cycloalkyl, optionally substituted aryl, optionally substituted heterocyclyl, optionally substituted heteroaryl, COR27, CSR27, OR27, and NHR27, wherein each R27 is independently optionally substituted alkyl, optionally substituted alkylamino, optionally substituted cycloalkyl, optionally substituted aryl, optionally substituted heterocyclyl, or optionally substituted heteroaryl; and each AA is independently an amino acid; n is an integer from 0 to 25; L4 is the remaining portion of linker L2 or is absent; T is said targeting moiety; wherein the NH group bonded to R10 in Formula X forms a junction peptide bond JPB with AA1 in Formula VI, wherein the JPB is enzymatically cleavable, and wherein AA1 AA, taken together comprises an amino acid sequence capable of facilitating enyzmatic cleavage of said JPB <a href=https://acialis.sbs>cialis generic cost</a> can i get a refund for it